This is the information for the Employee that is highlighted in the Tree view. When adding fill in as much information as you can. You can edit this information at any time. First and Last name are required fields.
The Active box must be checked for an Employee to be able to login to the system. When an Employee leaves, just untick this box and Save and the Employee will no longer be able to login.
Permissions determines what an Employee can do in My Pricebook. Clicking on the different 'Apply... Defaults' buttons checks and un-checks the different parts of My Pricebook. You can also manually change the checkmarks by clicking on them. When there is no checkmark, the Employee that is highlighted will not have access to that part of My Pricebook.